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Dr. Nancy
Paiva, Adjunct Professor e-mail: nlpaiva@noble.org |
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Area of Interest and Research Goals: My program is shifting its focus from determining the biochemistry and regulatory mechanisms of phytoalexin biosynthesis to actively altering the secondary metabolite profiles of plants, by genetic engineering or, to a lesser extent, via screening for mutants. In the past we needed to collect various tools; now we are applying them. The long term goal is to determine the importance of these metabolites in plant-microbe or plant-insect interactions.gens. |
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| Selected Publications:
Paiva, N.L., Sun, Y., Dixon, R.A., VanEtten, H.D. and Hrazdina, G. 1994. Molecular cloning of isoflavone reductase from pea (Pisum sativum L.): Evidence for a 3R-isoflavone intermediate in (+)-pisatin biosynthesis. Archives of Biochemistry and Biophysics 213:501-510 Paiva, N.L., Oommen, A., Harrison, M.J. and Dixon, R.A. 1994. Regulation of isoflavonoid metabolism in alfalfa. Plant Cell, Tissue and Organ Culture 38:213-220. (also published in "Primary and Secondary Metabolism of Plants and Cell Cultures III", (1995) Schripsema, J. and Verpoorte, R., eds., Kluwer Academic publishers, Boston, pp 213-220. Dixon, R.A., Harrison, M.J. and Paiva, N.L. 1994. Biochemical and molecular analysis of defense responses in legumes: an overview. Proceedings of the 1st European Nitrogen Fixation Conference, eds G.B. Hiss and G. Endre, Officing Press, Szeged, pp 195-198. Dixon, R.A., Bhattacharyya, M.K. and Paiva, N.L. 1995. Engineering disease resistance in plants: an overview. In "Advanced methods in Plant Pathology", Singh, R.P. and Singh, U.S., eds., CRC Press, Boca Raton, pp 249-270. Dixon, R.A., and Paiva, N.L. 1995. Stress-induced phenylpropanoid metabolism. Plant Cell 7:1085-1097. Pallas, J.A., Paiva, N.L., Lamb, C.J. and Dixon, R.A. 1996. Tobacco plants epigenetically suppressed in phenylalanine ammonia-lyase do not develop systemic acquired resistance in response to infection by tobacco mosaic virus. Plant Journal 10:281-293. Bianchini, G.M., Stermer, B.A. and Paiva, N.L. 1996. Induction of early mevalonate pathway enzymes and biosynthesis of end products in potato (Solanum tuberosum L.) tubers by wounding and elicitation. Phytochemistry 42:1563-1571. Howles, P.A., Seqalt, V.J.H., Paiva, N.L., Lamb, C.J., Elkind, Y., Bate, N.J. and Dixon, R.A. 1996. Overexpression of phenylalanine ammonia-lyase in transgenic tobacco plants reveals control points for flux into phenylpropanoid synthesis. Plant Physiology 112:1617-1624. McKhann, H.I., Paiva, N.L., Dixon, R.A., and Hirsch, A.M. 1997. Chalcone synthase transcripts are detected in alfalfa root hairs following inoculation with wild-type Rhizobium meliloti. Molecular Plant-Microbe Interactions 10:50-58. |
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| For more information
contact:
Dr. Nancy L. Paiva Phone: (405)223-5810 |
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