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BIO5
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- 1. UA Plant Scientist Receives $2.17 Million
- This story is from the Fall, 2007 issue of Advancing Arizona, p. 8, available online at http://www.uafoundation.org/pdf/AdvancingAz.pdf.
The Science Foundation Arizona has awarded University of Arizona BIO5 Institute member David Galbraith and High Throughput Genomics, a Tucson-based company, a two-year, $2.17 million grant to fund the Chemical Genomics and Translational Research Center.
The center, a collaboration between Galbraith and BIO5 and the company, known as HTG, will develop HTG’s quantitative Nuclease Protection Assay platform into a high density microarray. The platform will improve the quality and speed of biomarker and target identification, validation and subsequent screening and optimization of agricultural and pharmaceutical compounds.
The Science Foundation Arizona will provide $1 million for the first year of the grant and, based on the achievements of specific milestones, an additional $1 million for the second year. An additional $171,550 is designated as a UA institutional
allowance.
The center also will receive in-kind funding from HTG and BIO5, potentially bringing the funding total to $6 million over two years.
The advanced technology of the platform, known as qNPA, will help scientists identify changes in normal gene expression, such as abnormalities caused by disease as well as beneficial and adverse changes in gene activity caused by drugs.
The qNPA platform will be validated and applied to a diverse set of BIO5 projects conducted by UA faculty, including identifying agricultural chemicals that will reduce the cost of producing ethanol for biofuels, and identifying molecular changes that occur when cells become cancerous. - Updated: November 29, 2007
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