Cell cycle regulation by glycosylation of signal molecules
Glycosylation is a critical metabolic pathway with diverse roles in cellular processes. In plants, glycosylation of phytochemicals by the addition of glucose or other sugars generally results in enhanced water solubility and lower chemical reactivity. Reversible glycosylation of hormones such as auxin and cytokinin may be important in 'homeostasis' for the regulation of physiologically active hormone levels. In other cases, glycosylation of plant hormones might accompany or introduce irreversible deactivation.
We have established evidence that certain signal molecules, whose activity is regulated by glycosylation, are endogenous plant cell cycle regulators . The signal molecules are thought to be a metabolic product(s) of a newly identified enzyme, a n UDP-glycosyltransferase ( Ps UGT 1 ), which plays a critical role in plant growth and development. Identification of signal molecule(s) and its receptor complex is a major theme in the current project.
|For more information:||Dr. Ho-Hyung Woo, firstname.lastname@example.org|