B.S., University of California, Irvine 1986
Ph.D., University of California, Los Angeles 1996
Postdoctoral Training, University of California, Berkeley 1996-2000
Research
Interests
Molecular
Genetics of Developmental Regulatory Pathways in Arabidopsis: We
are interested in understanding the regulatory processes that mediate
fertilization and the initiation of seed development. The plant
life cycle alternates between a diploid sporophyte generation and
a haploid gametophyte generation. The angiosperm female gametophyte
is critical to the reproductive process. It is the structure within
which egg cell production and fertilization take place. Using the
model plant Arabidopsis thaliana, we are focusing on two specific
processes: (1) development of the female gametophyte and (2) control
of seed initiation by gene-regulatory complexes before and after
fertilization. For example, we are using a combination of expression-based
analyses and genetic resources of Arabidopsis to identify major
gene-regulatory networks involved in the differentiation of the
female gametophyte cell types. Similarly, using biochemical, molecular
and genetic approaches, we are identifying components of the Polycomb-group
complexes that mediate epigenetic repression of gene expression
before fertilization.
Teaching
PL
S/MCB/ECOL 440/540—Plant Growth & Development
PL
S684—Advanced Topics in Plant Developmental Biology |
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Nodine, M.D., Yadegari, R., and Tax, F.E. (2007).
RPK1 and TOAD2 Are Two Receptor-like Kinases Redundantly Required
for Arabidopsis Embryonic Pattern Formation. Dev Cell 12, 943-956.
Coury,
D.A., Zhang, C.Q., Ko, A., Skaggs, M.I., Christensen, C.A., Drews,
G.N., Feldmann, K.A., and Yadegari, R. (2007).
Segregation distortion in Arabidopsis gametophytic factor 1 (gfa1)
mutants is caused by a deficiency of an essential RNA splicing factor.
Sexual Plant Reproduction 20, 87-97.
Wang,
D., Tyson, M.D., Jackson, S.S., and Yadegari, R.
(2006). Partially redundant functions of two SET-domain polycomb-group
proteins in controlling initiation of seed development in Arabidopsis.
PNAS 103, 13244-13249.
Dinneny,
J.R., Yadegari, R., Fischer, R.L., Yanofsky, M.F.,
and Weigel, D. (2004). The role of JAGGED in shaping lateral organs.
Development 131, 1101-1110.
Yadegari,
R., and Drews, G.N. (2004). Female gametophyte development.
Plant Cell 16 Suppl, S133-141.
Drews,
G. N., and Yadegari, R. (2002). Development and
function of the angiosperm female gametophyte. Annu Rev Genet 36,
99-124. |
